A fading celebrity decides to use a black market drug, a cell-replicating substance that temporarily creates a younger, better version of herself.

By coincidence rather then by design the swiss chemist Albert Hofmann makes a sensational discovery in the spring of 1943. He realizes that he is dealing with a powerful molecule that will have an impact not only on the scientific world. THE SUBSTANCE – is an investigation into our troubled relation with LSD. Told from its beginnings until today.

After developing an addiction to the substance he uses to kill bugs, an exterminator accidentally murders his wife and becomes involved in a secret government plot being orchestrated by giant bugs in an Islamic port town in Africa.

A drive-in favorite, this sci-fi classic follows teenagers Steve and his best girl, Jane, as they try to protect their hometown from a gelatinous alien life form that engulfs everything it touches. The first to discover the substance and live to tell about it, Steve and Jane witness the blob destroying an elderly man and grow to a terrifying size. But no one else has seen the goo, and policeman Dave refuses to believe the kids without proof.

While dining out with friends, Sy suggests the difficulty of separating comedy from tragedy. To illustrate his point, he tells his guests two parallel stories about Melinda ; both versions have the same basic elements, but one take on her state of affairs leans toward levity, while the other is full of anguish. Each story involves Melinda coping with a recent divorce through substance abuse while beginning a romantic relationship with a close friend’s husband.

A vicious beaver blankets the jungle with a dangerous pink substance that explodes when coming into contact with water. With the rainy season approaching, the miscellaneous team of animals must hurry to find the antidote.

Amy Winehouse, an English singer-songwriter known for her distinct vocals and musical blend, rose to fame but battled substance abuse and mental health struggles. she passed away in 2011 at age 27, leaving a powerful musical legacy.

Beleaguered professor Ned Brainard has already run into a pile of misfortunes with his discovery of the super-elastic substance “Flubber.” Now he hopes to have better luck with a gravity-busting derivative he’s dubbed “Flubbergas.” Ned’s experiments, constantly hampered by government obstruction, earn the consternation of his wife, Betsy. But a game-winning modification to a football uniform may help Ned make the case for his fantastic new invention.

In recent days, Rome has been the scene of an unusual event: when it rains, the manholes exhale a dense steam of unknown origin and composition. No one knows that those who breathe in the mysterious substance will have to deal with what they repress, their darkest instincts, their anger. Not even the Morel family. Since Cristina’s death in an accident a year earlier, the love of her husband Thomas and their son Enrico has given way to a forced cohabitation, while the youngest of the family, Barbara, would only like to see them united again as they were before. The accident could have been avoided, both Thomas and Enrico know it. Instead of taking responsibility and moving on, they stopped talking to each other. Now they are two souls full of rage, trapped in a Rome that resembles them: dark, nervous, on the verge of exploding.

A group of friends go to a secluded town to do a short film project but when they take an addictive substance that promised to bring them to cloud nine, they get to experience hell instead.

Andre Ward’s journey from the streets of Oakland to the International Boxing Hall of Fame. Facing an all-too familiar series of obstacles including substance abuse, the loss of a parent, drug dealing and teen pregnancy, how Ward faced that adversity is what separates him from the rest. Fight after fight he defied the odds and silenced his critics. And then, guided by faith and devotion, he walked away – choosing his role as a father and a husband over his boxing career.

Everyyear,venomoussnakeskillover100,000peopleandhospitalizethousandsmore.Despitethisstaggeringnumber,thedeadlyvenomisalsousedtosavelivesintheproductionofanti-venom.There’saproblemthough:anti-venomsuppliesaredwindlingeveryyear,makingthestakesevenhigherforbraveprofessionalswhoharvestthisequallydeadlyandprecioussubstance.NewDiscoveryseriesVENOMHUNTERSwillfollowfourbraveteamsofexpertsnakehunterswhohavethegutsandskillstochasedowntheworld’smostvenomoussnakesandcollectthishighlytoxicliquid.Eachteamhasuniquemotivationsandthrivesonthethrillofthehunt,buttheyallsharethesamegoal:savingthelivesofothers.TheseriespremiereofVENOMHUNTERSdebutsWednesday,Feb.17at10/9conDiscovery.FromtheFloridaswamplandsandtheplainsofOklahoma,totheAustralianoutbackandArizonadesert,thefearlessvenomexpertswillputtheirlivesonthelinetotrack,catchandharvestthevenom…WrittenbyFrank

Set over the course of four days in modernday Dublin, this Irish dramedy revolves around two petty-criminal cousins released from Mountjoy Prison. Weed is keen to pursue fashion, if only he can break his substance addiction. Ste wants to build a better life for himself, his girlfriend and their daughter. But that’s before they get drawn into a robbery that goes spectacularly wrong in Cathal Nally’s energetic feature debut.

A mother helps her daughter work through four crucial days of recovery from substance abuse.

1 in 5 Americans are diagnosed with mental illness every year. Suicide is the second most common cause of death in the US for youth aged 15-24, and kills over 48,300 in the US and 800,000 people globally per year. Drug overdose kills 81,000 in the US annually. The autoimmune disorder epidemic affects 24 million people in the US alone. What is going on? The interconnected epidemics of anxiety, chronic illness and substance abuse are, according to Dr Gabor Maté, normal – but not in the way you might think.

When Chris, the coolest guy in school discovers that Roxy sees through his popularity and good looks, he enlists Cy to reverse catfish her-letting him take over his social media accounts to add substance to his style.

The story of three lifelong friends who overcame domestic violence, substance abuse and depression to form Life of Agony, one of the most influential bands in its genre, led by the very first openly transgender singer. Through the success of their groundbreaking 1993 debut “River Runs Red”, hailed by Rolling Stone as “One of the Greatest Metal Albums of All Time”, they channeled their cumulative life stories into a soundtrack for a broken generation. This new found fame allowed them to suppress the tragedies of their past, but in its wake new obstacles arose.

A professional hockey player who is only happy when he is miserable signs a long-term contract that covers his entire career only to ruin it in his first year due to substance abuse and alcoholism. He rides his good luck in the final month of the final year of his contract when he gets a last chance at redemption in the seventh game of the finals.

A pro ball player with a substance abuse problem is forced into rehab in his hometown, finding new hope when he gets honest about his checkered past, and takes on coaching duties for a misfit Little League team

An Irish sports journalist becomes convinced that Lance Armstrong’s performances during the Tour de France victories are fueled by banned substances. With this conviction, he starts hunting for evidence that will expose Armstrong.

In the year 10,191, the world is at war for control of the desert planet Dune – the only place where the time-travel substance ‘Spice’ can be found. But when one leader gives up control, it’s only so he can stage a coup with some unsavory characters.

The insurgence of substance abuse among the young in the Indian state of Punjab through the stories of a rock star, a migrant laborer, a doctor and a policeman.

Professor Phillip Brainard, an absent minded professor, works with his assistant Weebo, trying to create a substance that’s a new source of energy and that will save Medfield College where his sweetheart Sara is the president. He has missed his wedding twice, and on the afternoon of his third wedding, Professor Brainard creates flubber, which allows objects to fly through the air.

A controversial portrayal of teens in New York City which exposes a deeply disturbing world of sex and substance abuse. The film focuses on a sexually reckless, freckle-faced boy named Telly, whose goal is to have sex with as many different girls as he can. When Jenny, a girl who has had sex only once, tests positive for HIV, she knows she contracted the disease from Telly. When Jenny discovers that Telly’s idea of “safe sex” is to only have sex with virgins, and is continuing to pass the disease onto other unsuspecting girls, Jenny makes it her business to try to stop him.

Basket-case network news producer Jane Craig falls for new reporter Tom Grunnick, a pretty boy who represents the trend towards entertainment news she despises. Aaron Altman, a talented but plain correspondent, carries an unrequited torch for Jane. Sparks fly between the three as the network prepares for big changes, and both the news and Jane must decide between style and substance.

A documentary about the legendary series of nationally televised debates in 1968 between two great public intellectuals, the liberal Gore Vidal and the conservative William F. Buckley Jr. Intended as commentary on the issues of their day, these vitriolic and explosive encounters came to define the modern era of public discourse in the media, marking the big bang moment of our contemporary media landscape when spectacle trumped content and argument replaced substance. Best of Enemies delves into the entangled biographies of these two great thinkers and luxuriates in the language and the theater of their debates, begging the question, ‘What has television done to the way we discuss politics in our democracy today?’

Substance-addicted Hollywood actress Suzanne Vale is on the skids. After a spell at a detox centre her film company insists as a condition of continuing to employ her that she live with her mother Doris Mann, herself once a star and now a champion drinker. Such a set-up is bad news for Suzanne who has struggled for years to get out of her mother’s shadow, and who finds her mother still treats her like a child. Despite these problems – and further ones to do with the men in in her life – Suzanne can begin to see the funny side of her situation, and it also starts to occur to her that not only do daughters have mothers, mothers do too.

“Ring of Fire” recounts June’s meteoric rise to fame with The Carter Family, considered the First Family of country music, before breaking out on her own to perform, when she would become a legend in her own right. Taking a personal look at June’s first two marriages, life with her daughters and touching relationship with her son, the movie showcases her infamous courtship with Cash and June’s heroic role in saving his life during his battles with substance abuse, as well as how her unwavering faith in God, confidence and talent has taught lessons to generations.

Ex-undercover cop turned biker Rane, witnesses the brutal murder of his pregnant wife by his crew who have learned about his old policemen days. Upon his exit from the hospital, he arms himself to the teeth and goes on an substance fueled, psychotic rampage, in the name of retribution

A giant asteroid is heading toward Earth so some astronauts disembark from a nearby space station to blow it up. The mission is successful, and they return to the station unknowingly bringing back a gooey green substance that mutates into one-eyed tentacled monsters that feed off electricity. Soon the station is crawling with them, and people are being zapped left and right!

This ifilm is a new documentary that explores the controversial use of marijuana and the evolution of mainstream society. From a dangerous narcotic, listed as a Schedule 1 Drug substance since the 1970s, to the rush to decriminalize it today. What has changed and why? What will the cannabis industry look like in five years? Will it retain its integrity as a homegrown industry or be co-opted by Big Business? Experts, growers, celebrities and politicians weigh in on the future of Cannabusiness

CERN and the University of California-Santa Barbara are collaborating in the search for the elusive substance that physicists and astronomers believe holds the universe together — dark matter. Where is this search now in the realm of particle physics and what comes next?

Enzo Ceccotti comes into contact with a radioactive substance, then accidently discovers he has superpowers. A touchy, navel-gazing introvert, he’s sure his new capabilities will do wonders for his life of crime, but that all changes when he meets Alessia, who’s convinced he’s the hero from the famous Japanese comic strip, Steel Jeeg Robot.

A Blanc-Biehn production centered around the idea of a governmentally designed drug created to help correct or strategically alter perceptions gathered during times of trauma or stress. Slated as being a substance that may help solve issues with everything from racial tensions, PTSD and geopolitic battles, first a focused study is needed to see how people respond to treatment and what dosages might be needed. Four couples are chosen to test this drug, and soon find their memories and sanity challenged.

Lowriders vs. Zombies from Space is a comedic Sci-Fi/Horror film set in the city of San Antonio, TX. It is in the style of the classical 80s-90s “B” low budget movies of that era with a modern take. The story follows a group of friends and lowriders throughout the day as they prepare to go to a dance that night. During the dance a strange alien substance is introduced and infects several people turning them into alien zombies. After that all hell breaks loose inside and outside of the dance hall. Lowriders must survive the vicious attack of these alien zombies using their resources, the cars.

A dysfunctional family awake on Christmas morning to discover they’re sealed inside their house by a mysterious black substance. On television, a single line of text reads: “Stay Indoors and Await Further Instructions.”

An adaptation of Tao Lin’s beloved cult novel “Taipei”. As one relationship collapses, another blooms for Erin, swept into the world of Paul Chen, a mysterious, charismatic author. When he proposes documenting every aspect of their courtship in an epic laptop-filmed “documentary”, the couple enter into a performative bad romance, fueled by substances and sleepless nights.

When a substance abuse counsellor gets arrested for a DUI and returns to her hometown of Niagara Falls, she learns that her estranged father is dying of cancer and wants her to form a bond with her teenage half-sister that she’s never met.

‘The Shadow of the Sun’ draws upon Derek Jarman’s interest with alchemical processes as a metaphor for reprocessing Super-8 film. Jarman once described film’s union of light and matter as “an alchemical conjunction” and experimented throughout his career with creating dream symbolism through the superimposition of image and action. Originally called English Apocalypse, the film’s final title is derived from a 17th Century alchemical text that used the phrase as a synonym for the philosopher’s stone – the highly sought substance that turns base metals into gold and silver. The film was intended as a step toward the idea of an ambient video, that like its musical counterpart, was designed to enhance an environment.

A wealthy high powered woman suffers a horrible tragedy after which she descends into substance abuse,turning her back on her family. She later discovers that someone close to her may be behind her subsequent abduction and kidnapping.