Twenty years after they were frozen, Abe, Cleo, JFK, and Joan suddenly find themselves thrust into the modern world, where they must navigate a fresh batch of historical clones, dramatic love triangles, and a formidable new foe.

13 years after being impregnated by Satan, a reluctant mother, Laura, and her Antichrist daughter, Chrissy, attempt to live an ordinary life in Delaware, but are constantly thwarted by monstrous forces, including Satan, who yearns for custody of his daughter’s soul.