The story follows a family of inbreeds who have been afflicted by a genetic disorder known as ‘Merrye syndrome’, named after the family in which the disorder developed. This malady causes its victims to enter a state of age regression that starts at the age of ten and continues throughout the remainder of the person’s life, rendering them with the intelligence of a child. The final generation of the family has been entrusted to the care of the family chauffeur (Lon Chaney Jr), and all is well for these odd people until a greedy branch of the family decides that they want to relieve the family of its home. Mental illness has always, and will always be, a fascinating subject for horror movies as it probes into the unknown and Spider Baby makes best use of that fact.
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Jack Deebs is a cartoonist who is due to be released from jail. His comic book “Cool World” describes a zany world populated by “doodles” (cartoon characters) and “noids” (humanoids). What Jack didn’t realize is that Cool World really does exist, and a “doodle” scientist has just perfected a machine which links Cool World with our world. Intrigued at seeing his creating come to life, Jack is nonetheless wary as he knows that not everything in Cool World is exactly friendly.
Portland book editor Natalie Holland has chosen the wrong guy – another underachiever – once again. With her life going nowhere fast, she accepts a job offer from publisher and friend Avery Goldstein and moves to Los Angeles. A woman of depth and principle, Portland chic Natalie is a fish out of water in LA. Things only get worse when she learns she’s been hired to edit the latest romance novel from bestselling author Beverly Wilcox, a powerful, glamorous and intimidating figure straight out of “The Devil Wears Prada”.
Ping, a young nobleman, has retired from the service of the crown in order to become a musician. He becomes a student of Master Duang, a famous musician. Master Duang owns a mysterious drum called Perng Mang, which has the power to bring success or death to people. Meanwhile, an arrogant musician called Muan tries to convince all the students to leave Master Duang. Some students follow his advice and end up dying horrible deaths which defy explanation. When Master Duang is defeated by Muan, he calls for Ping to inherit his musical knowledge and gives him the Perng Mang. Ping is told about the secret of Perng Mang and that it was made from a woman’s skin. The woman’s name was Thip, the same name of the woman he has fallen in love with.
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Two young business partners are invited to a week-long yachting voyage with a potential investor. At night, Jennifer’s dreams begin to bleed into reality as the others realize that Jennifer may have unknowingly brought something on-board.
A young man born out of an incestuous relationship, after enduring an emotionally scarring childhood, gives in to the dark side of Satanic forces and becomes a weapon of evil. He kills with such ferocity that he becomes the main target of the L.A.P.D. Detective Russell Logan engages in a battle of wits with Channing in life and after death. It appears that Channing can’t be stopped, but Logan has a few tricks of his own to match Channing’s -“First Power”.
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