A disease carried by common cockroaches is killing Manhattan children. In an effort to stop the epidemic an entomologist, Susan Tyler, creates a mutant breed of insect that secretes a fluid to kill the roaches. This mutant breed was engineered to die after one generation, but three years later Susan finds out that the species has survived and evolved into a large, gruesome monster that can mimic human form.
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After Marnie Watson kills her abusive husband in self-defense, she is condemned to house arrest… only to discover that the house is possessed by the enraged and violent spirit of her dead husband.
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Young newlyweds Irene and Daniel make the mistake of picking up a hitchhiker — and soon find themselves taken hostage by three dangerous criminals.
A rap group on the verge of signing their first record deal is the city’s only hope in a battle with a giant mutating snake monster.