The feature length version of the serial by the same name. A mystical medicine arrow, the key to a lost gold treasure, is lost in one of many Indian attacks. It is recovered by the only two survivors, a Major and his daughter, who become the targets of those who wish to possess it. General George Armstrong Custer and army scout Kid Cardigan attempt to stop the ensuing war over the arrow, but fail in their efforts, which becomes the historic Custer’s Last Stand.
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Johnny Hart (Rod Cameron) is on the run from the law after killing one of the men who shot his partner. He passes through a town and stops at a saloon owned by singer Lorena Dumont (Yvonne de Carlo). The two seem a good, albeit tempestuous match, although Johnny has no plans to marry — Lorena has other ideas and a shotgun wedding ensues.
Phoebe Titus is a tough, swaggering pioneer woman, but her ways become decidedly more feminine when she falls for California bound Peter Muncie. But Peter won’t be distracted from his journey and Phoebe is left alone and plenty busy with villains Jefferson Carteret and Lazarus Ward plotting at every turn to destroy her freighting company. She has not seen the last of Peter, however.
Centers on Missy’s adopted daughter Belinda Tyler as she follows her dream. Belinda wants to be a doctor, but this time period does not look kindly on women with careers, especially one in the medical field. But Belinda is a strong-minded woman and deeply wants a career as a doctor. She manages to prove her abilities while assisting the local doctor and caring for an old woman who recently experienced a stroke. Belinda nurses her back to health and helps her regain the use of her arm again. Belinda also meets the nephew of their deceased neighbor. Drew comes to town to get his uncle’s farm in shape to sell. After that he intends on returning to New York to join his father’s law practice. He has no desire to stay in this small, unsophisticated town. But after meeting Belinda he has second thoughts. Belinda also feels something for Drew, but she is conflicted because she wants to be a doctor…
Dowanhowee, a Native American woman, evades the notorious Dutch Wilder Gang by escaping into the uncharted Black Wood Forest. Once inside, they quickly discover they must help each other for they have unknowingly awaken an ancient ravenous creature, known as The Wendigo.
Johnny Mack Brown was recruited by Chet Norman, the owner of a stagecoach line, to end the heist perpetrated by a mysterious knight who plays strange notes with a hiss of money before robbing them.
When his cattlemen abandon him for the gold fields, rancher Wil Andersen is forced to take on a collection of young boys as his cowboys in order to get his herd to market in time to avoid financial disaster. The boys learn to do a man’s job under Andersen’s tutelage; however, neither Andersen nor the boys know that a gang of cattle thieves is stalking them.
For thirty years, Marshall Matt Dillon fought to preserve the law in Dodge City… now, he’s wanted for murder and fighting to clear his name. Three deputies ride up with a warrant for Dillon’s arrest, a wealthy mine operator has been gunned down in cold blood and an eyewitness says Dillon was the murderer.
In this sequel, Lillian has been adopted and it’s several years later. Annie, married and pregnant, visits her fellow doctor friend, Dr. Owen. Dr Owen desperately wants a baby, but seems unable to become pregnant. Lillian finds a love interest, an assistant to her adoptive dad, the latter has become quite overprotective.
Hogan, on his way to do some reconnaissance for a future mission to capture a French fort, encounters Sister Sara, a nun in trouble. Before he knows it, Hogan is accompanying Sister Sara in the dangerous frontier while she seeks to achieve a hidden goal.
Chester Wooley (Lou Costello) and Duke Egan (Bud Abbott) are traveling salesmen who make a stopover in Wagon Gap, Montana while enroute to California. During the stopover, a notorious criminal, Fred Hawkins, is murdered, and the two are charged with the crime.