As Emily struggles to fit in at home and at school, she discovers a small red puppy who is destined to become her best friend. When Clifford magically undergoes one heck of a growth spurt, becomes a gigantic dog and attracts the attention of a genetics company, Emily and her Uncle Casey have to fight the forces of greed as they go on the run across New York City. Along the way, Clifford affects the lives of everyone around him and teaches Emily and her uncle the true meaning of acceptance and unconditional love.
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Jerry, a misfit Mafia henchman, is assigned the low-level job of keeping an eye on Gino, a shoe repairman fingered by the Mob to confess to a murder he didn’t commit. But Gino’s mistaken for a Mafia boss, and the two are suddenly catapulted to the highest levels of mobster status. Only friendship will see them through this dangerous adventure alive!
After the 1860s Wild West, a group of misfit settlers – including ex-doctor Phil Taylor, prostitute Belle, and homosexual bookseller Julian – decide they cannot live in their current situation in the west. They hire a grizzled alcoholic wagon master by the name of James Harlow to take them on a journey back to their hometowns in the East.
An evil Duke attempts to kill and collect the blood of a royal family of European vampires in order to become all powerful. The only surviving member of the family travels to Hong Kong, only to complicate his struggle by falling in love with a mortal girl who just happens to have a vampire hunter for a brother.
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