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A tense standoff between law enforcement and the survivors erupts into a bloodbath; in a bid to evade a vicious breed of vampire, Axel and Scarlett find themselves hunted like prey.
As the group struggles with the disappearance of one of its own, they accept sanctuary in a town run by its Sheriff and his troops; Dmitri inches closer to achieving his darkest goal.
Vanessa faces off with Dmitri; Axel fights against becoming a full-fledged vampire; Sam tracks Mohamad, Flesh and Lucky; Scab tries to enlist a fierce group of vampires to join Dmitri.
Vanessa’s past rushes back to confront her in an unexpected way; a secret that Doc has been protecting is revealed; and in a bid to bolster his power, Dmitri sends Scab on an impossible mission.
Vanessa faces off against Sam in a bloody showdown; Dmitri hears news that sends him on a warpath after Vanessa; Flesh, Mohamad and Lucky take desperate steps to save their lives.
Vanessa encounters a group of vampires whose gruesome methods bring savagery to a new level; the Juvenile Delinquents continue their game of cat and mouse with Sam and that has deadly consequences.
Vanessa makes a horrific decision to save her daughter; Axel and a former ally struggle to survive in the wild; a group of juvenile delinquents come face to face with a sadistic vampire.
Vanessa fights to get her daughter out of the citadel; Dmitri and Antanasia hatch a plot to stop Vanessa; Mohamad risks his life to save Vanessa and Dylan.
Vanessa and Mohamad search for Dylan as Dmitri’s citadel crumbles around them; Flesh acquires an unexpected ally in one of the Resistance Fighters; Taka clashes with the Vampire Elite.
Now in Dmitri and Rebecca’s clutches, Vanessa learns secrets from her past and finds herself at a crossroads; Flesh and the Resistance accelerate their timeline to rescue Vanessa; Mohamad and Sheema finally come to blows over their allegiances.
While on the road to a vampire-controlled camp, Vanessa and Mohamad find themselves in a dangerous game of cat-and-mouse against Sam. Sheema discovers a secret that can bring down the ghetto-cell of the Resistance, while Julius takes a clandestine meeting with Dmitri. Ultimately, Vanessa and Mohamad walk into a trap that places one of them in great peril.
Vanessa and the group take shelter in Susan’s family farm, where drastic action is taken against Sam; Rebecca’s latest experiment to create Daywalkers fails, and Dmitri’s patience grows thin.
Still reeling from the dire events of ‘The Farm’, Vanessa and the group find refuge among a band of humans who have bargained with vampires for peace. Their leader, however, appears to be hiding a terrible secret. Meanwhile, the true serial killer among Vanessa’s group is finally revealed.
The group is trapped inside an underground lab for military experiments, and Vanessa discovers that Axel has been hiding a secret about her past; Mohamad befriends a girl who doesn’t fear vampires; Rebecca makes a calculated play.
Axel leads the surviving members of their group towards his old military base for shelter but finds it abandoned and in disrepair. With vampires closing in all around them, Axel decides they need a safer refuge and decides to go underground. Separated from Vanessa and the group, Mohamad tries to catch up while navigating hostile territory.
Vanessa and Axel lead the others in the hospital’s last stand against a siege by Julius and his vampire soldiers. Later when Dmitri’s vampire ‘Death Squad’ arrives, it looks like civil war is brewing among the two vampire factions.
Vanessa and Susan are pursued through the sewers by mutated feral vampires and arrive back at the safety of the hospital only to find the aftermath of a hostile takeover. Vanessa hatches a plan to take it back by force.
Vanessa, now in the clutches of Julius and his vampire brood, is forced to demonstrate her powers; the refugees discover a serial killer among the residents, and plot to wrestle control from Axel.
Vanessa and Mohamad head into the vampire-controlled streets in search of Vanessa’s daughter; Cynthia is found dead at the hospital, and Doc thinks her apparent suicide is actually a deliberate murder; Vanessa is captured by vampires.
The hospital’s power source is damaged, jeopardizing the protective UV lights. Vanessa and Axel head into Seattle to scavenge parts, leaving the others to fight against the vampires amongst themselves.
In the days leading up to “The Rising,” Vanessa is attacked and left for dead by an intruder. When Doc discovers anomalies in Vanessa’s bloodwork, Axel and the marines come to retrieve the body, only to become marooned in the hospital when all hell breaks loose outside the building.
Vanessa Helsing, a distant relative of the famous vampire hunter Abraham Van Helsing is resurrected, but soon realizes that the world was conquered by vampires. Tya is humanity’s last hope to lead people to regain their lost.
Following a stunning betrayal to their team, Brian and the FBI race to stop an NZT-enabled Sands and his associates from orchestrating an international incident. Also, Brian experiences devastating side effects when his NZT immunity starts to wear off.
When NZT floods the streets of New York City and threatens to become a national epidemic, the FBI partners with the DOJ in a city-wide manhunt to find the lab producing the drug. Also, Brian has trouble adjusting to his new reality when he lacks the resources to continue searching for Piper.
When Rebecca learns the truth about her father’s death, she takes NZT for the first time and uses it to seek justice for his murder. Also, Sands makes a dangerous move against Brian to ensure the success of his new initiative.
Brian’s double life unravels when Senator Morra makes contact just as Brian’s placed under 24-hour surveillance by the FBI following his rogue trip to Russia. Also, Mike and Ike tell an already suspicious Rebecca about Brian’s off-book interaction with Morra’s henchman, Sands.
When Brian’s closest relationships implode due to his inability to cut ties with Eddie Morra, he goes rogue from the FBI to free himself from the senator’s control. In Russia, he searches for Piper, Morra’s former associate turned adversary, and her alternative NZT vaccine. Also, Rebecca comes closer to discovering Brian’s connection to NZT and Senator Morra.
Brian and Rebecca are placed under quarantine by the CDC after being exposed to an unknown substance after investigating a citywide blackout. Also, trust issues arise after Rebecca catches Brian using his secret stash of NZT.
When Sands, Senator Morra’s deadly representative, enlists Brian’s help to eliminate an immediate threat he needs to keep secret from the politician, Brian learns Sands’ dangerous and shocking past. Also, Brian’s sister, Rachel, scrambles to cover up his abrupt side mission with Sands when the FBI can’t reach him regarding a new case.
After a list with the real identities of undercover bureau operatives leaks, Brian develops a personal connection with FBI Agent Lucy Church, a tenacious rule-breaker, when he helps her finish a field case before she’s exposed. Also, Sands makes a surprising move to end Rebecca’s investigation into Senator Morra.
When a developer at the tech think tank Brian frequents is murdered, he and Rebecca interview the robotic version of the victim that she created before her death for clues to the killer’s identity. Also, Brian screens agents for a position to join Mike and Ike as his third bodyguard.
Brian embarks on his first FBI field assignment when he travels to Quantico to lend his skills to the bureau unit that catches serial killers. However, the trip takes a negative turn when Brian realizes the man he’s working with may have put away an innocent person in the career-making case that made him a renowned profiler. Also, Brian tries to stay one step ahead of Rebecca as she comes closer to discovering Senator Morra’s connection to NZT.
When an assassin makes an attempt on Senator Edward Morra’s life, Brian is ordered to sabotage the FBI’s investigation into it in order to prevent exposing the Senator’s connection to NZT. As Brian and Morra’s fates become further intertwined, Brian is faced with how far he’s willing to go to protect the politician.
When Agent Casey Rooks and his SWAT team skim 80 NZT pills for themselves from the recovery of stolen inventory, it starts an internal investigation that is viewed through the shifting perspectives of Brian’s immediate circle at the FBI.
When Boyle’s former military buddy is accused of murder and blames it on the loss of control of his prosthetic arm, Boyle asks Brian to help determine if the artificial limb was hacked. Also, Brian’s father demands he stop working for the FBI.
Brian offers to use NZT to capture the FBI’s “Ten Most Wanted” criminals in two weeks, in exchange for Naz giving him his own personal work “headquarters” at the agency. Also, the secretive nature of Brian’s new life working for the Bureau creates a rift between him and his father.
When Naz is detained on suspicion of funding terrorism, Brian and Rebecca’s efforts to clear her name lead them to Naz’s daughter, Ava, who reveals a family secret Naz is keeping from the FBI.
When Brian calls in sick for a day off from the FBI, the CIA abducts him from home to borrow his NZT-enhanced capabilities for a black ops mission. As the operation becomes increasingly dangerous, Brian finds himself without FBI support in a situation that’s spiraling out of control.
When Brian begins to experience the side effects of NZT again, Senator Morra demands he betrays Rebecca in exchange for another inoculation. Also, Brian secretly looks for an alternate cure for himself while he works with Rebecca outside FBI parameters to find the creators of NZT.
Brian learns a shocking secret about Rebecca’s late father but worries that telling her will land him in legal trouble. Also, Brian accidentally meddles in Rebecca’s personal life while learning self-defense from her secret boyfriend, FBI Agent Casey Rooks.