Five-0 must find a kidnapped patient infected with a contagious and lethal strain of bird flu which the culprits intend to weaponize.

A neurosurgeon is assassinated just before performing a surgery. The investigation uncovers the truth behind the disappearance of four reform school boys over 40 years ago. Meanwhile, McGarrett’s beloved Mercury Marquis is stolen by an unlikely culprit.

When a tourist is killed after unknowingly transporting a stolen Van Gogh, an undercover Kono and Chin enter the world of black market priceless art and are taken hostage. Also, McGarrett asks Iron Chef Masaharu Morimoto to help train Kamekona to beat Chef Sam Choy in a shrimp cook-off.

With the help of an ex-HPD officer-turned private detective, Five-0 tries to solve the homicide of a woman who was working for a hula dancing company that is actually a front for an escort service.

It’s Christmas in Hawaii and Five-0 travels to the Big Island, where Max is forced to work with a rival medical examiner after a cowboy is poisoned. Meanwhile, McGarrett pressures Danny into stealing a Christmas tree.

While the team investigates a couple’s murder in which their sons are the prime suspects, McGarrett is shocked when Aunt Deb returns to the island with her new fiancé.

When McGarrett is kidnapped by Wo Fat, he experiences what would have happened to the team if they had taken a very different path, on the 100th episode.

It’s Halloween and Five-0 must track down a serial killer who is copying murders depicted in a cult slasher film. Meanwhile, McGarrett must help Jerry after he is kidnapped by the counterfeiters he has been tracking.

On the fourth anniversary of his father’s death, McGarrett meets a woman who helps him reopen the last unsolved case his dad worked on before he died.

When a Detroit hit man is taken out by one of his colleagues on the streets of Oahu, Five-0 is shocked to learn the killer’s surprising motives. Meanwhile, Chin puts his career on the line to help Danny get the money he needs to save his brother’s life.

Three young women rob a tour bus, but things go horribly wrong when a man is killed and the women unknowingly steal something of great value that puts their lives in danger.

While a Navy Seal is on a secret mission, his young daughter is kidnapped; Danny must find $18.5 million in order to save his brother.

The island of O’ahu goes on lockdown when Five-0 hunts a terrorist who starts using weaponized drones on civilians. Meanwhile, McGarrett and Danno must go for a mandated review with a psychologist, resulting in a session which looks a lot like couples therapy.

When Grover’s daughter is kidnapped by an old nemesis, he is forced to help steal $100 million in order to get her back. Meanwhile, Wo Fat escapes prison and heads back to Oahu.

McGarrett and Catherine travel overseas to Afghanistan to stop the Taliban from harming a young boy whose family saved Catherine’s life years ago.

The investigation of a murdered pool cleaner leads the Five-0 team to a possible terrorist cell of radicalized students plotting an attack on U.S. soil.

Five-0 is set up when a bad tip leads them to an abandoned building that is rigged to explode with McGarrett and Danny trapped inside.

Five-0 investigates when the daughter of a macadamia nut tycoon is murdered with a stiletto heel during Chin’s high school reunion.

A man is shot as his daughter is abducted; Danny tries to reunite his parents; Jerry finds a code on McGarrett’s champ box.

A triple homicide is linked to a secret, downed Chinese satellite; Danny’s mother goes on a ride-along with Grover.

A real estate agent is found dead inside the walls of one of his listings. Meanwhile, Danny’s mother makes an unexpected visit and brings with her some shocking news.

An escaped convict who wants Five-0 to prove his innocence abducts Danny and McGarrett; Grace punches a person at school.

Chin is questioned about his father’s murder and how his relationship with Malia and her family could have adversely affected the investigation.

Captain Grover is aided by McGarrett in his search for a friend who has disappeared, after it seems like he’s committed murder. Kono persists in her quest to find Adam.

An investigation involving a potential serial killer puts Chin’s life in danger; Grace and Danny find a mysterious puzzle box.

The attempted murder of a Pearl Harbor veteran leads Five-0 to use decades old evidence to investigate a deadly crime committed within the internment camps on Oahu during World War II.

As Thanksgiving approaches, Five-0 investigates the murder of a secret service agent just as the President travels to Oahu. Also, McGarrett’s Aunt Deb visits, bringing with her a shocking secret.

McGarrett and Grover must work together to protect national security after they are tasked by the Governor to serve a warrant to a young computer hacker.

While working the murder case of an undercover ATF agent, McGarrett and the Five-0 team are tasked with watching Mary’s newly adopted baby after she gets sick.

When Halloween comes to Hawaii and a zombie-like man is shot, Five-0 races to stop a madman who is conducting experiments on humans.

As Catherine’s seemingly harmless surveillance job takes a deadly turn, Adam considers making the ultimate sacrifice to save Kono.

Five-0 investigates the murder of a wedding crasher, and their prime suspect is the runaway bride. Meanwhile, Danny makes a big decision regarding his relationship with Gabby.

A conspiracy theorist helps Five-0 when a missing artifact is the key to solving a double murder.

As the Five-0 team members investigate a murder, they are led to a Texas ranger who came to Hawaii to look for his daughter; Adam and Kono fight to stay alive.

After McGarrett and Wo Fat narrowly escape from maximum security, gunmen storm Five-0 headquarters, compromising Kono and Adam’s secret location in Hong Kong and forcing McGarrett to break the law and turn on his own in order to find a kidnapped Catherine.

When a plane lands on Oahu with four bodies on board and a missing terrorist detainee, the CIA tasks Five-0 with finding him before he carries out an attack on U.S. soil. Meanwhile, Kono is on the run from the police for a murder she did not commit, and McGarrett’s prison visit to Wo Fat ends with a shocking discovery.

McGarrett must help his mother execute a covert op to retrieve an incriminating microfiche. Meanwhile, Kono’s life is in danger when she closes in on Adam’s secret.

When the body of a young girl who was kidnapped 10 years earlier is discovered, Five-0 must hunt down the kidnappers who have now taken their next victim. Meanwhile, Kono asks Catherine for a favor that could damage her relationship with Adam.

Five-0 allows a talk show host and her crew to follow them for the day, but the investigation turns dangerous when they have a run-in with Wo Fat.