A powerless Clark is trapped in the “Phantom Zone” surrounded by the criminals his father imprisoned there. However, an unexpected ally comes to his aid. Meanwhile, Zod in Lex’s body advances his plan to transform Earth into a new Krypton, while using Lana to produce an heir.

Professor Fine has unleashed a virus that will kill millions. Clark must put a stop to him, while Lex wonders what happens when he will tell Lana his newest secret.

Clark and Martha are both visited by Jonathan’s ghost, who warns them about Lionel and claims that Clark must kill him to stop him. Meanwhile Fine will do whatever it takes to get the vaccine from Lex.

Clark saves a man who in gratitude decides to help Clark in return…by using his ability to turn invisible and his skill as a hitman to kill Lex so Clark can reunite with Lana. And Clark and Lana finally square off about Lana’s new relationship.

Lionel is taken hostage by a masked man who forces him to play elaborate games for the prize of staying alive. Martha goes to confront Lionel after Clark tells her Lionel knows his secret and becomes a part of the game herself, fighting for her life.

Clark befriends a little girl who has the ability to telekinetically shatter glass, then comes to her aid when it’s believed she killed her mother in a brutal stabbing attack. Meanwhile Lex and Lana grow closer together and Chloe finds out about it.

Distraught over her break-up with Clark, Lana goes to a rogue medical student who experiments with a dangerous kryptonite-based serum that allows people to flat-line but see their dead loved ones. Lana attempts to see her dead parents using the serum and when Clark returns from Honduras to help her, the doctor injects him with the serum and Clark speaks with his dead father…who warns him that Lionel knows his secret. Meanwhile, Lionel continues working to get closer to Martha, and Lex has a near-death vision of his mother.

Clark is hypnotized by a woman who uses a supposedly magical charm to control others – he reveals his super powers and is sent to kill Lex. Meanwhile, Lex has tracked down the missing Professor Fine and plans to confront him, unaware that Clark is coming to murder him.

Clark finds himself up against Lex when he befriends Victor Stone, a half-machine, half-human subject who escapes from LuthorCorp with the aid of a sympathetic doctor.

Chloe is possessed by the spirit of a young girl whose body is sealed in the Talon’s walls, and goes searching for the girl’s killer while Clark and Lois try to track her down.

Clark discovers that the new assistant at the Daily Planet, a bespectacled, bumbling woman named Andrea, is actually a mysterious female vigilante who stalks Suicide Slum. Her path crosses Clark’s as they both seek the same criminal. Meanwhile, Clark’s bottled-up grief threatens to get the best of him and LuthorCorp experiences a shakeup.

Clark reveals his secret to Lana, Jonathan and Lex learn the results of the senatorial election, and there is a tragic car accident on the highway that takes the life of someone Clark loves, forcing Clark to appeal to Jor-El for help.

Lex and Lana are at the mercy of a deranged Smallville deputy who plans to keep them captive until Lex reveals the location of the Kryptonian spaceship. Meanwhile, the Kents can’t see eye-to-eye on campaign financing.

The Senatorial race between Jonathan and Lex heats up when Jonathan receives an anonymous threat warning him to drop out of the election. When Clark finds Jonathan badly beaten he determines to find the attackers. Lois is thrown into the mix when she is captured and she is forced to assassinate Jonathan during his speech.

Lex considers whether to turn an operative loose to obtain or fake damaging information against Jonathan to upset his Senatorial race. But when Lex is shot, he falls into a coma and is visited by the ghost of his mother, who shows him what his life could be like if he frees himself from his father. Meanwhile, Clark helps deliver Christmas presents.

When Martha comes down with a strange disease, Professor Fine convinces Clark that Jor-El is responsible and that the Fortress must be trying to eliminate the father of Kal-El. But Professor Fine has an ulterior motive which comes to fruition when they arrive.

Clark gives into paranoid delusions brought on by exposure to new “silver” kryptonite, and Professor Fine is the only one who can save him… before he kills Lana.

Jonathan’s oldest friend, Senator Jack Jennings, comes to Smallville looking for support in his re-election campaign, but is framed for the murder of his mistress, requiring Lois to go undercover as a stripper.

Lana joins a sorority to get housing for her last-minute college registration, but the sisters have a deadly agenda which involves turning Lana into a vampire like themselves and sending her against Clark. Meanwhile, Chloe applies to become an intern at the Daily Planet and runs up against the editor-in-chief, Pauline Kahn.

At a party at Crater Lake, Lois is saved from drowning by Arthur “A.C.” Curry. Arthur has incredible swimming abilities, but also a secret agenda aimed at…Lex. Meanwhile, Professor Fine discussed Lex’s weapons-manfucturing operations with Clark.

A krypto-mutant, Gabriel, hacks into missile codes and prepares to eliminate krypto-mutants in Smallville once and for all. A powerless Clark confronts him and is shot, and only Jor-El can save him.

Clark faces off against three Belle Reve prisoners who plan to force him to help break into the sanitarium’s mysterious “Level Three.”

Lana greets two new Kryptonian arrivals from the ship, Nam-Ek and Aethyr, and their presence poses a grave danger to Clark and his family & friends.

After a nightmare, Clark goes to the cave to confront his father Jor-El. Jor-El warns that the crystals have fallen into human hands and have triggered a new meteor shower which will annihilate the Earth unless he reunites the three crystals. Meanwhile, Lex helps Lana, who has apparently commited murder, but then turns against her to get possession of her Kryptonian stone. As disaster looms, Chloe and Lois try to find Lana while Clark attempts to reassemble the stones, and Jason returns to make things unpleasant for the Kents.

Clark must stop the school photographer after he sets up a fake high school and uses his ability to petrify people to kidnap students – including Chloe and Lana – to keep the glory days of high school going forever. Meanwhile, Lex and Lionel are kidnapped and tortured by the Teagues in an effort to find the Kryptonian artifact, revealing that…Lana has it.

Checking out a crater in a cornfield, Clark and Lana discover a baby with no parents and take him back to the Kent farm. However, when the baby, Evan, ages from a newborn to a 7-year-old in less than a day, it becomes clear he is aging at a rapid rate and they turn to Lex for help. Meanwhile, Genevieve suspects Lex has the Chinese Kryptonian artifact and orders Lionel to either recover it…or risk putting Lex in danger of his life.

When a boy who can make people lose their memories robs the Talon, Clark goes after him but gets total amnesia. Chloe finds out what happened and has to tutor Clark in the use of his superpowers and make sure he doesn’t accidentally reveal his secret. While Clark, Chloe, and Lois try to track down Kevin, Clark takes advantage of his “new life” to ask Lana on a date. And Lex tries to turn Clark’s memory loss to his advantage by getting him to reveal the secret of the caves.

On the eve of the Smallville High School Prom, stuck-up candidate for Prom Queen Dawn Stiles is pulled into a coma when she is involved in a car crash into a ravine filled with dozens of chunks of kryptonite. While her body lies in a coma, Dawn finds her spirit allowed to possess the bodies of others, where she can continue her quest to become Prom Queen. As a result, Martha, her body possessed by Dawn, flirts with Clark and asks him to the Prom, Lana attempts to electrocute the ex-boyfriend who dumped Dawn, Lois goes all-out to ensure she and Clark go to Prom together, and Chloe attempts to set fire to the school on Prom night.

A black kryptonite explosion splits Lex in two and his evil side – Alexander – is released. Alexander imprisons Lex in the mansion then gives full vent to his evil side – he threatens to evict Lana from the Talon unless she becomes his mate, jousts with Lionel, and tries to kill Clark and Chloe when they figure out his secret.

Lucy Lane, Lois’ younger sister, comes to Smallville but Clark catches her stealing money from the Talon to pay off a European crime syndicate. Lex offers to help but everything is not what it seems. Meanwhile, a thief breaks into Lana’s apartment and steals the crystal, and Jason suspects Lionel.

After Clark receives a message from the recently-deceased Dr. Swann, he and Lana follow Jason and Lex to China in search of one of the kryptonian crystals. Lana is tortured, causing Isabelle to emerge and wreck havoc in her search for the crystal.

Lois accidentally hits a dog and brings it back to the farm to heal, but Clark quickly realizes it has super-strength. He investigates and discovers it was part of an aborted LuthorCorp experiment…and that robbers are using the dogs to help them steal money. Meanwhile, Lana wonders what Jason is up to with his mother, and Jason is forced to ask Genevieve a few questions of his own.

Clark is approached by Met U for recruitment and meets Geoff, a former Smallville resident. It soon becomes apparent that he is using his powers to paralyze anybody who gets in his way…including Lois.

When a mysterious killer strikes at both Lana and Jason, Alicia is the leading suspect and even Clark comes to doubt her innocence. Feeling betrayed, she secretly tricks Clark into revealing his powers in front of one of his friends. And Genevieve returns to town with an offer for Lex, who in turn has an offer for Jason.

Alicia (from “Obsession”) is supposedly cured and returns to Smallville to start things back up with Clark. When she pushes for more and he turns reluctant, Alicia expoess him to red kryptonite, and the two go off to Las Vegas to get married. Meanwhile, Lana questions whether sex may prove the key to winning Jason back.

A Luthorcorp experiment is released into the atmosphere – a toxin that causes its victims to hallucinate their worst fear. Chloe, Clark, Lana, and Jason all fall fictim to the toxin, and Lex, desperate to find a cure, takes a dangerous antidote. Meanwhile, Lionel is released from prison and his conviction overturned thanks to a mysterious benefactor.

Lex is accused of killing a young woman and and Clark turns to Lionel for help. Meanwhile, Lana has a dream of her ancestor and a mysterious second woman – a dead ringer for Jason’s mother Genevieve, who arrives to visit her son and his new girlfriend.

Lana reads a spell book belonging to her 17th century ancestor, the witch Isabelle, and becomes possessed by her spirit. Isabelle resurrects her other two witches and together they seek out the kryptonian crystals, using their magic to render Clark powerless.

Mikail Mxyzptlk, a foreign exchange student and bookie, has the power to control others and uses it to sabotage football games, including the one Clark is quarterbacking. Clark and Chloe figure out his secret, but he threatens to kill Chloe unless Clark throws the next game. Mikail came to Smallville via LuthorCorp, and Lex will do almost anything to learn his secret.

Clark is drawn to the state penitentery by one of the kryptonian crystals, which Lionel is using to switch bodies with Lex. Clark intervenes and Lionel enters his body instead. While Lionel uses his newfound super-powers to regain his lost fortune and alienate Clark’s friend, Clark must convince his parents that he is the “real” Clark and reverse the processs, while avoiding murderous convicts.