A family takes a journey across the globe on a strange and amazing flying machine, experiencing a series of adventures along the way.

As Emily struggles to fit in at home and at school, she discovers a small red puppy who is destined to become her best friend. When Clifford magically undergoes one heck of a growth spurt, becomes a gigantic dog and attracts the attention of a genetics company, Emily and her Uncle Casey have to fight the forces of greed as they go on the run across New York City. Along the way, Clifford affects the lives of everyone around him and teaches Emily and her uncle the true meaning of acceptance and unconditional love.

Restless and ready for adventure, four suburban bikers leave the safety of their subdivision and head out on the open road. But complications ensue when they cross paths with an intimidating band of New Mexico bikers known as the Del Fuegos.

Through a series of misunderstandings, Alvin, Simon and Theodore come to believe that Dave is going to propose to his new girlfriend in New York City – and dump them. They have three days to get to him and stop the proposal.

Van Wilder has been attending college for far too many years and is scared to graduate, but Van’s father eventually realizes what is going on. When he stops paying his son’s tuition fees, Van must come up with the money if he wants to stay in college, so he and his friends come up with a great fund-raising idea – throwing parties. However, when the college magazine finds out and reporter, Gwen is sent to do a story on Van Wilder, things get a little complicated.

Charlie and Dan have been best friends and business partners for thirty years; their Manhattan public relations firm is on the verge of a huge business deal with a Japanese company. With two weeks to sew up the contract, Dan gets a surprise: a woman he married on a drunken impulse nearly nine years before (annulled the next day) shows up to tell him he’s the father of her twins, now seven, and she’ll be in jail for 14 days for a political protest. Dan volunteers to keep the tykes, although he’s up tight and clueless. With Charlie’s help is there any way they can be dad and uncle, meet the kids’ expectations, and still land the account?

A commitment-averse man frantically hits the dating scene after his girlfriend starts pressuring him to pop the question.