As they enter sophomore year at Monster High, Clawdeen Wolf, Draculaura and Frankie Stein face new students, new powers, and an even bigger threat that could not only tear their friendship apart but could change the world forever.

Corey (Fred Savage) refuses to let his emotionally disturbed younger brother Jimmy (Luke Edwards) be institutionalized, and the two run away together. They soon join forces with a resourceful girl (Jenny Lewis), who notices that Jimmy has a special talent: he is a “wizard” at video games and can achieve the high score on absolutely everything he plays. Evading their parents and a sinister bounty hunter, the trio head for a climactic showdown at the national video game championships in California.