A young college student arrives in a sleepy Massachusetts town to research witchcraft; during her stay at an eerie inn, she discovers a startling secret about the town and its inhabitants.

A strange series of solar flares proves fatal for inhabitants of the Earth, except for the fortunate few who are somehow immune from the effects. Animals go insane and human beings turn to white powder, leaving behind only empty clothing. A handful of survivors attempt to rebuild their lives on the de-populated Earth.

Wisecracking reporter Carl Kolchak investigates a string of gruesome murders in Las Vegas. It seems that each victim has been bitten in the neck and drained of all their blood. Kolchak is sure that it is a vampire. He’s hot on the trail, but nobody believes him. His editor thinks he’s nuts and the police think he’s a hindrance in the investigation, so Kolchak takes matters into his own hand.