A mentally ill man searches New York for his missing eight year old daughter. He recreates her steps each day hoping for some clue to her disappearance, until he meets and befriends a woman with a daughter the same age. Could she help him with the missing piece of the puzzle?

Italian immigrant Francesca Cabrini arrives in 1889 New York City and is greeted by disease, crime, and impoverished children. Cabrini sets off on a daring mission to convince the hostile mayor to secure housing and healthcare for society’s most vulnerable. With broken English and poor health, Cabrini uses her entrepreneurial mind to build an empire of hope unlike anything the world had ever seen.