An international assassin known as ‘The Jackal’ is employed by disgruntled French generals to kill President Charles de Gaulle, with a dedicated gendarme on the assassin’s trail.

Famous organist Anton Phibes is horribly disfigured in an automobile accident while rushing to the side of his sick wife and presumed to be dead. Once Phibes learns that his wife died on the operating table, he is convinced the doctors are responsible and begins exacting his revenge on all those involved.