In 35,000 BC, the tribe of the Dirty Hairs is at war against the tribe of the Clean Hairs for eight hundred years, trying to get their shampoo. The chief of the Dirty Hairs sends his daughter Guy disguised to the enemy tribe to get some shampoo for his tribe. When the healer of the Clean Hairs tribe surprisingly kills two cavemen of his tribe, their imbecile chief assigns Pierre with curled hair and Pierre blonde to investigate the murder and find the criminal.

In November 2015, a series of unprecedented and deadly attacks hits Paris. The anti-terrorist police led by Heloise and her chief commander Fred – face an unprecedented level of pressure: in a race against the clock, they must find the perpetrators of the attacks as quickly as possible before they can strike again, travelling across Europe and beyond in one of the biggest manhunts in history.