In the second episode of the trilogy Fantômas kidnaps distinguished scientist professor Marchand with the aim to develop a super weapon that will enable him to menace the world. Fantômas is also planning to abduct a second scientist, professor Lefebvre.

Fantômas is a man of many disguises. He uses maquillage as a weapon. He can impersonate anyone using an array of masks and can create endless confusion by constantly changing his appearance.