Maggie and Jimmy have never met, but they keep showing up in each other’s dreams. As they navigate memories, traumas, hopes and desires in sleep and the waking world, they’ll discover the truth of their linked destiny with the help of a dream detective, a sleep scientist and the poet Walt Whitman himself.

Dr. Caine, the murdering dentist from the original movie, has escaped from the mental hospital where he has been since being caught. Hoping to resume a normal life, he makes his way to a quiet Midwestern town under a false name and takes on the responsibilities of the town dentist Things are starting to look up for Caine, until the day when he catches his new love in the arms of someone else. Just as in the first movie, this sends him back over the edge and into another homicidal rampage, with his unfortunate patients bearing the brunt of his hostility.

When young Poindexter “Fool” Williams breaks into the creepy, immense old home of his family’s greedy and uncaring landlords, he uncovers a disturbing scenario underneath the stairs.

Trevor Blackburn is accused of murdering his girlfriend, Faith, in a brutal ritual. He’s sentenced to live in an experimental rehabilitation community and falls into a coma. When he wakes up, he meets the mysterious Dr. Elk, who tortures Trevor in an attempt to learn the whereabouts of a powerful occult book. As other patients start to disappear, Trevor begins to wonder who and where he really is.