When a virus leaks from a top-secret facility, turning all resident researchers into ravenous zombies and their lab animals into mutated hounds from hell, the government sends in an elite military task force to contain the outbreak. Alice and Rain are charged with leading the mission. But they only have three hours before the pathogen becomes airborne and infects the world.

In the near future, Uffizi and Luke travel to the remote reaches of war torn Romania to rescue Elizabeth and finish the vampire once and for all. Along the way, they encounter TV news journalist and a corps of rebels trying to fight the vampire uprising which plagues their country.

Sequel to Dracula 2000. Father Uffizi [Jason Scott Lee] hunts vampires. He travels the world to behead them with his bullwhip, but his ultimate goal is to find the first vampire, Dracula (revealed as Judas Iscariot in Dracula 2000), absolve Dracula’s sins against Jesus, set his soul free, and end his unholy existence. So, when Dracula’s charred body turns up in the New Orleans morgue, Uffizi heads there. Medical students, Liz Blaine [Diane Neal] and Luke [Jason London] are charged with autopsying the body. When they open the abdominal cavity, they find that the liver and other organs are white, suggesting to Luke that the person did not produce his own blood but got it elsewhere, i.e., a vampire.

After the American Army shot down a UFO in 1947, generations of elite commandos were secretly trained to deal with the aliens’ feared return. However, the extra-terrestrials never came back and the elite force was disbanded. Sixty-six years after the Roswell crash, the aliens are invading Earth and only the over-the-hill retired commandos can stop them.