Worlds collide at an awkward dinner party in 1959 New England. Tables turn when a progressive biracial couple attends dinner at the imposing home of an unexceptional artist and questionable psychiatrist. By daybreak, they find themselves pawns in a cynical game that exposes the cracks in their facades.

At the age of ten, Henry James Hermin, a boy who was conceived in a petri-dish and raised by his feminist mother, follows a string of Post-It notes in hopes of finding his biological father.