A lone-wolf scientist sequestered in a mansion near a small desert town arouses the suspicion of the town’s doctor when his lab assistant is found dead from a case of acromegaly which took only four days to develop. As the doctor investigates, aided by the scientist’s new, and very female, assistant, they discover that, far worse, something much larger and hungrier than it ever should be, is devouring local cattle – and humans – in increasingly large quantities.

An atomic bomb test in the Arctic Circle unfreezes a hibernating fictional dinosaur, a Rhedosaurus, that begins to wreak havoc in New York City.

Frank Johnson, sole witness to a gangland murder, goes into hiding and is trailed by Police Inspector Ferris, on the theory that Frank is trying to escape from possible retaliation. Frank’s wife, Eleanor, suspects he is actually running away from their unsuccessful marriage. Aided by a newspaperman, Danny Leggett, Eleanor sets out to locate her husband. The killer is also looking for him, and keeps close tabs on Eleanor.

En route to Normandy, an American and a British officer reminisce in flashback about their romances with the same woman.