A young girl tormented by the tragedies of her past is brought in for questioning by the police over the death of a man, who she claims to be a demon. Detective Beckett realizes this is the same girl he made a broken promise to seven years ago that he’d find the monster that raped and murdered her 12 year old sister.

12 strangers are held against their will as each of them must go along with the rules if they are to get the cure for a killer virus which infects them all.