When a group of gifted college students run a secret teleportation experiment, they accidentally open a portal to another dimension, trapping them in Hell. One by one they are hunted, tortured and killed by the denizens of Hell who are bent on stealing their souls.

Buddy Solitaire is a struggling comedian on the late night circuit. The only job he can get is teaching comedy to the mentally ill. Buddy discovers, however, that by helping these patients, he can get closer and closer to healing himself.