When Blade’s mother was bitten by a vampire during pregnancy, she did not know that she gave her son a special gift while dying: All the good vampire attributes in combination with the best human skills. Blade and his mentor Whistler battle an evil vampire rebel (Deacon Frost) who plans to take over the outdated vampire council, capture Blade and resurrect voracious blood god La Magra.

A killer known as Ghostface begins killing off teenagers, and as the body count begins rising, one girl and her friends find themselves contemplating the ‘rules’ of horror films as they find themselves living in a real-life one.