An expert in paranormal Emily Strand takes her team on their last ghost hunt to explain the supernatural. She finds her team terrorized in one of Americas most haunted places. Escaping from the supernatural is their only chance to survive.

Three inept night watchmen, aided by a young rookie and a fearless tabloid journalist, fight an epic battle to save their lives. A mistaken warehouse delivery unleashes a horde of hungry vampires, and these unlikely heroes must not only save themselves but also stop the scourge that threatens to take over the city of Baltimore.