After the death of their super powered villainous boss, low-level henchpeople Beatrix, Cain and Harold are left destitute living in an abandoned grocery store. Not content with the situation they find themselves in, Beatrix is determined for them to strike out on their own and take over the world by any means necessary.

Ryûhei Sasaki (Teruyuki Kagawa) is keeping a secret from his wife, Megumi (Kyôko Koizumi), and his two teenage sons. Even though he leaves the house every day, he’s not really going to work. He’s going to an employment office. He recently lost his job due to outsourcing, but is determined to find another position, all while supporting an old friend who is also out of work. But when Megumi accidentally finds out Ryûhei’s secret and doesn’t tell him, her trust in him, and their marriage, suffers.

The Laughter Life follows a week in the life of the young comedians who write and star in Studio C, a popular sketch comedy television show that has garnered over 1 billion views on YouTube.