Charles Dexter Ward’s wife enlists the help of a private detective to find out what her husband is up to in a remote cabin owned by his family for centuries. The husband is a chemical engineer, and the smells from his experiments (and the delivery of what appear to be human remains at all hours) are beginning to arouse the attention of neighbors and local law enforcement officials.

Struggling to rebuild their lives, a former tennis star and a recent divorcee decide to isolate themselves from the world in a quest for true “oneness”; as their affair descends into savagery, his father must fight to save them before they disappear completely into madness.

Impatient to have a child, an infertile couple seeks help at a sperm bank and are thrilled when the procedure works. But their joy is cut short after they discover the donor is a psychopath willing to kill anyone who stands between him and his baby.