In the Eighteenth Century, in a small village in Ireland, Redmond Barry is a young farm boy in love with his cousin Nora Brady. When Nora engages to the British Captain John Quin, Barry challenges him for a duel of pistols. He wins and escapes to Dublin, but is robbed on the road. Without any other alternative, Barry joins the British Army to fight in the Seven Years War.

Blackmailing a young couple to assist with his horrific experiments the Baron, desperate for vital medical data, abducts a man from an insane asylum. On route the abductee dies and the Baron and his assistant transplant his brain into a corpse. The creature is tormented by a trapped soul in an alien shell and, after a visit to his wife who violently rejects his monstrous form, the creature wrecks his revenge on the perpetrator of his misery: Baron Frankenstein.