Larry Flynt is the hedonistically obnoxious, but indomitable, publisher of Hustler magazine. The film recounts his struggle to make an honest living publishing his girlie magazine and how it changes into a battle to protect the freedom of speech for all people.

A reality TV program selects six contestants to participate in a free-for-all, no holds barred deathmatch, where they must skillfully outwit and kill each other in order to be the last person alive.