When a family visits Grandma’s house on Christmas Eve, they leave their dog at home alone. And when burglars try to take the presents from under the tree, the dog must use every trick it knows to stop them.

Manny has moved to a new school, and it’s not easy to fit in. After wishing he had more friends, Manny finds a mysterious collar and puts it on Rufus, the family dog. Suddenly, Rufus turns into a boy! Manny’s not sure what to do, so he enrolls Rufus in school. When the other students notice Rufus’s silly dog antics — chasing squirrels, eating without utensils, asking for belly rubs, and catching a soccer ball with his mouth — he immediately becomes the most popular kid around. Manny is jealous of his new best friend but eventually learns that a dog’s loyalty to his owner always comes first.

Rufus is a dog but turns into a human with a pendant. He meets a girl named Kat who asks him to go out. Kat is a cat who can also turn into a human as well.