Since the 1960s, a disproportionate number of the population in and around Nome, Alaska, have gone missing. Despite FBI investigations, the disappearances remain a mystery. Dr. Abigail Tyler, a psychologist, may be on the verge of blowing the unsolved cases wide open when, during the course of treating her patients, she finds evidence of alien abductions.

Laura Ullman, a single mother, kills her abusive ex-boyfriend and turns the gun on her son when he threatens to call the police. Paul leaves home to start a better life and falls for Ashley, a young woman looking for direction in her life, unaware of his past troubles.