A young woman struggling with addiction comes into possession of an ancient puzzle box, unaware that its purpose is to summon the Cenobites, a group of sadistic supernatural beings from another dimension.

Before their eventual team-up with Scooby and the gang, bright and optimistic Daphne and whip-smart and analytical Velma are both mystery-solving teens who are best friends but have only met online – until now. Daphne has just transferred to Velma’s school, Ridge Valley High, an incredible tech-savvy institute with all the latest gadgets provided by the school’s benefactor, tech billionaire Tobias Bloom. And while competition is fierce among the students for a coveted internship at Bloom Innovative, Daphne and Velma dig beyond all the gadgets and tech to investigate what is causing some of the brightest students in school to disappear – only to emerge again in a zombie-fied state.