In debt to their volatile drug dealer, best friends, Denise and Johnny, agree to a sketchy job to pay off their last hit. After breaking into a decrepit stash house to steal a bag of mysterious drugs, escape proves more troublesome, as the pair find themselves trapped inside with a madman. With no way out and not one to miss an opportunity, Johnny smokes the new drug and promptly travels into the past, triggering alarming new events in the future. Separated through time, Denise is left alone to confront her past, their dealer’s real identity, and her very own existence.

Two best friends and recovering addicts embark on a frantic chase through New York City to stop the woman they are both in love with from killing her ex-boyfriend.

This movie is a stark portrayal of life among a group of heroin addicts who hang out in Needle Park in New York City. Played against this setting is a low-key love story between Bobby, a young addict and small-time hustler, and Helen, a homeless girl who finds in her relationship with Bobby the stability she craves.

At the beginning of a nightly Alcoholics Anonymous meeting, Jim seems particularly troubled. His sponsor encourages him to talk that night, the first time in seven months, so he does – and leaves the meeting right after. As Jim wanders the night, searching for some solace in his old stomping grounds, bars and parks where he bought drugs, the meeting goes on, and we hear the stories of survivors and addicts – some, like Louis, who claim to have wandered in looking for choir practice, who don’t call themselves alcoholic, and others, like Joseph, whose drinking almost caused the death of his child – as they talk about their lives at the meeting

Jane’s lover Dax overdoses on heroin. Wanting to kill the pain of loss, Jane does dope for the first time and is soon on the way to addiction herself. She then discovers that drug users are being haunted by the ghosts of dead addicts. Soon she’s being followed by her dead boyfriend Dax as well as other thirsty spirits. Jane meets Rick, a young man with his own similar story. Rick is being tormented too…by the ghost of his overdosed girlfriend Azami, the most dangerous of the junkie vampire ghosts. Jane returns to her apartment after one night of nonstop terror. She goes into her bedroom and finds someone sleeping face down in her bed. Not getting a response, Jane turns over the body…