Mark Fallon, with partner Kansas John Polly, tries to introduce honest gambling on the riverboats. His first success makes enemies of the crooked gamblers and of fair Angelique Dureau, whose necklace he won. Later in New Orleans, Mark befriends Angelique’s father, but she still affects to despise him as his gambling career brings him wealth. Duelling, tragedy, and romantic complications follow.

Gerry is a talented but down-on-his-luck gambler whose fortunes begin to change when he meets Curtis, a younger, highly charismatic poker player. The two strike up an immediate friendship and Gerry quickly persuades his new friend to accompany him on a road trip to a legendary high stakes poker game in New Orleans. As they make their way down the Mississippi River, Gerry and Curtis manage to find themselves in just about every bar, racetrack, casino, and pool hall they can find, experiencing both incredible highs and dispiriting lows, but ultimately forging a deep and genuine bond that will stay with them long after their adventure is over.