A lone-wolf scientist sequestered in a mansion near a small desert town arouses the suspicion of the town’s doctor when his lab assistant is found dead from a case of acromegaly which took only four days to develop. As the doctor investigates, aided by the scientist’s new, and very female, assistant, they discover that, far worse, something much larger and hungrier than it ever should be, is devouring local cattle – and humans – in increasingly large quantities.

Giant lava breathing tarantulas – Lavalantulas – erupt out of ancient volcanos in the Santa Monica Mountains, raining death and destruction upon Los Angeles. With the City of Angels on the verge of incineration, only a washed up ‘90s action hero actor stands in the way of this monstrous swarm of bloodthirsty creatures who burn their victims alive.