A young woman with no strong religious beliefs, Frankie Paige begins having strange and violent experiences, showing signs of the wounds that Jesus received when crucified. When the Vatican gets word of Frankie’s situation, a high-ranking cardinal requests that the Rev. Andrew Kiernan investigate her case. Soon Kiernan realizes that very sinister forces are at work, and tries to rescue Frankie from the entity that is plaguing her.

Yong-hu, a world champion martial artist who believes in no God, only himself, suddenly develops stigmata on his palms. Visiting a church in hopes of healing the stigmata, he ends up saving Father Ahn, who falls into danger while performing an exorcism. In this way he learns of the power of the stigmata. As time passes Yong-hu accepts his new calling and begins saving people who are possessed by demons, but then he must prepare for a final confrontation with the evil Jisin, who ensnares people with the power of the devil.

Elwood, the now lone “Blues Brother” finally released from prison, is once again enlisted by Sister Mary Stigmata in her latest crusade to raise funds for a children’s hospital. Once again hitting the road to re-unite the band and win the big prize at the New Orleans Battle of the Bands, Elwood is pursued cross-country by the cops, led by Cabel the Curtis’ son

When a single mother begins to experience symptoms of the stigmata, she seeks the help of a local priest and nun to help her understand what is seen and unseen.