Michael Velayudham (Pawan Kalyan) is a chef specialized in Italian cuisine in Cape Town. He falls in love with Meera Sasthri (Trisha) – another Indian staying in Cape Town. Meera is a restoration specialist and she is moving to India. Since it is not possible to continue the relationship across the seas, they bid good bye to each other. Michael finds a local white girl (Danah) in Cape Town and Meera finds a local politician (Sonu Sood) back in India. The rest of the story is all about how their true love unites them despite them being so casual about their relationship. There is also another story dealing with Arjun Palwai (Pawan Kalyan) that runs parallel with a time difference of 30 years in Waranasi.

An ominous dream convinces 77-year-old Dayanand Kumar that his end could be near. He takes the news to his son Rajiv, knowing he wants to breathe his last in the holy city of Varanasi and end the cycle of rebirth, by attaining salvation. Being the dutiful son he is, Rajiv is left with no choice but to drop everything and make the journey with his stubborn father. Daya and Rajiv check into Mukti Bhawan (Hotel Salvation) in Varanasi, a guesthouse devoted to people who want to die there. But as the days go by, Rajiv struggles to juggle his responsibilities back home, while Daya starts to bloom in the hotel. Rajiv gives his father a shot at salvation but as family bonds are tested, he finds himself torn, and not knowing what he must do to keep his life together.