FBI Agent Will Graham, who retired after catching Hannibal Lecktor, returns to duty to engage in a risky cat-and-mouse game with Lecktor to capture a new killer.

After their boat capsizes in the Mediterranean Sea, a group of refugees are rescued by rich Europeans who offer them shelter on an idyllic island. But the miracle soon becomes a nightmare when the saviors turn into ruthless manhunters.

The human race is threatened by a powerful creature, and only the combined power of Superman, Batman, Wonder Woman, Green Lantern, Martian Manhunter and The Flash can stop it. But can they overcome their differences to thwart this enemy using the combined strength of their newly formed Justice League?