Jep Gambardella has seduced his way through the lavish nightlife of Rome for decades, but after his 65th birthday and a shock from the past, Jep looks past the nightclubs and parties to find a timeless landscape of absurd, exquisite beauty.

Gamba, a town mouse with a brave spirit decides to go on an adventure to discover the ocean. On his way, he meets a troubled child mouse, Chuta. He says his family and other mice on a nearby island have been killed by a clan of weasels, led by the terrifying Noroi. Gamba promises to save the island, his family and the other mice. He and his friends team up to defeat the evil Noroi and his clan.