Magic Tree House is a 2011 Japanese anime drama film based on the American children fantasy series of the same name. The film is directed by Hiroshi Nishikiori, and the film’s screenplay was adapted from the Japanese version of the novel series Magic Tree House by Ichiro Okouchi. The film stars actress Keiko Kitagawa as Jack, and also stars child actress Mana Ashida as Annie. Magic Tree House debuted at the 24th Tokyo International Film Festival on 23 October 2011. It was subsequently released in Japanese cinemas on 7 January 2012.

In the early 1990s, experiments were carried out secretly in Japan. Two different methods were used in the experiments. One method involved forcing stress upon expecting parents and when the baby was born, provoke the baby into mutations and develop their special abilities. The other method involved birth to babies having abilities of animals and insects. The special abilities were derived from gene manipulation. Subaru, Saya and others were born from those experiments.

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